Cell Therapy/ Cell-based therapies
There is an alarming increase in the number of cases of diabetes with the global prevalence rate at 9% for the year 2014. Around 387 million patients worldwide are suffering from diabetes, and this number is expected to increase by 50% by 2030. In particular, the South East Asian countries are affected most due to diabetes with projected 10% increase in diabetic patients by 2035. Studies over the past several years highlight that cell-based therapies involving adult stem and progenitor cells hold promise of rescuing the dying endothelium in diabetes. This novel therapeutic strategy involves stem cells obtained from a variety of sources, such as circulating endothelial progenitor cells, mesenchymal stromal cells (MSCs), embryonic stem cells, and inducible pluripotent stem cells (iPSCs).Studies over the past several years highlight that cell-based therapies involving adult stem and progenitor cells hold promise of rescuing the dying endothelium in diabetes. This novel therapeutic strategy involves stem cells obtained from a variety of sources, such as circulating endothelial progenitor cells, mesenchymal stromal cells (MSCs), embryonic stem cells, and inducible pluripotent stem cells (iPSCs).
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